Peer-Reviewed Publications

Cracan V*, Titov DV*, Sheng H, Grabarek Z, Mootha VK. Genetically encoded tool for manipulation of NADP+/NADPH ratio. Nature Chemical Biology. 2017 Aug 7. doi: 10.1038/nchembio.2454.

Titov DV*, Cracan V*, Goodman RP, Peng J, Grabarek Z, Mootha VK. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.  Science. 2016 Apr 8;352(6282):231-5.

Lewis-Smith D, Kamer KJ, Griffin H, Childs AM, Pysden K, Titov D, Duff J, Pyle A, Taylor RW, Yu-Wai-Man P, Ramesh V, Horvath R, Mootha VK, Chinnery PF. Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood. Neurol Genet. 2016 Mar 3;2(2):e59.

He QL*, Titov DV*, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angew Chem Int Ed Engl. 2015 Feb 2;54(6):1859-63.

Titov DV, Liu JO. Identification and validation of protein targets of bioactive small molecules. Bioorganic & medicinal chemistry 20 (6), 1902-1909.

Titov DV, Gilman B, He QL , Bhat S, Low WK, Dang Y, Smeaton M, et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature chemical biology 7 (3), 182-188.

Liu JO, Titov DV, Dang Y, He Q. Regulator of Ras Depalmitoylation and Retrograde Trafficking: A New Hat for FKBP. Molecular cell 41 (2), 131-133.

Ni Q, Titov DV, Zhang J. Analyzing protein kinase dynamics in living cells with FRET reporters. Methods 40 (3), 279-286.